ZEOLITIC IMIDAZOLATE FRAMEWORK-8-COATED SOLID-PHASE MICROEXTRACTION ARROW IN THE EXTRACTION OF AMINES

 

Hangzhen Lan, Tukka Rönkkö, Jevegni Parshintsev, Kari Hartonen, Marja-liisa Riekkola
Laboratory of Analytical Chemistry, Department of Chemistry, University of Helsinki, Finland
 
A new sorbent material for solid-phase micro extraction (SPME) Arrow was developed for quantitative enrichment of small amines from wastewater samples. The new coating was prepared by dipping stainless steel Arrow several times into a mixture of zeolitic imidazolate framework-8 (ZIF-8), poly(vinyl chloride) (PVC) and tetrahydrofuran (THF). Heating was necessary between each dipping cycle in order to improve the viscosity of the coating. The prepared Arrow was aged in high temperature and acidified by hydrochloride acid. Finally, the acidified arrow was dried before use. Coating preparation conditions, such as ZIF-8 to PVC proportion, number of dipping cycles and used treatment temperatures and times, were all optimized. Optimized coating was characterized by scanning electron microscope (SEM) and X-ray photoelectron spectroscopy (XPS). Extraction and desorption conditions, including extraction time, agitation speed, ionic strength, desorption temperature and time were carefully optimized. ZIF-8-coated arrow exhibited good extraction performance comparable with commercial Carboxen-1000 coated SPME Arrow, which is generally considered to be well suitable for the extraction of amines.

 

Hangzhen Lan

Education
 Bachelor of Science (2008-2012)
- Major: Food Quality and Safety
- School: Ningbo University.

 Master of Science (2012-2015)
- Major: Food Quality and Safety
- School: Ningbo University.
- Supervisor: Prof. Daodong Pan

 Doctor of Philosophy (2015 up to the present, degree expected in September 2019)
- Major: Analytical Chemistry
- School: University of Helsinki
- Supervisor: Prof. Marja-liisa Riekkola

Publications:

Lan H, Gan N, Pan D, et al. An automated solid-phase microextraction method based on magnetic molecularly imprinted polymer as fiber coating for detection of trace estrogens in milk powder, Journal of Chromatography A, 2014, 1331C: 10-18.

Lan H, Gan N, Pan D, et al. Development of a novel magnetic molecularly imprinted polymer coating using porous zeolite imidazolate framework-8 coated magnetic iron oxide as carrier for automated solid phase microextraction of estrogens in fish and pork samples, Journal of Chromatography A, 2014, 1365C: 35-44.

Li TH, Wang D, Lan H, et al. Determination of 17β-Estradiol Based on Electropolymerized-Molecularly Imprinted Polymer on Gold Nanoparticles-Graphene Modified Electrode. Advanced Materials Research, 2014, 881: 93-97.

Pan D, Gu Y, Lan H, et al. Functional graphene-gold nano-composite fabricated electrochemical biosensor for direct and rapid detection of bisphenol A. Analytica chimica acta, 2015, 853: 297-302.

Submitted manuscript:
Lan H, Pan D, Gan N, et al. Preparation of novel E-MOF-5 solid-phase microextraction coating by potential-controlled cathodic electrodeposition for analysis of trace exogenous estrogens in food samples.

Research Techniques and Skills
SPME fiber coatings preparation and automated SPME fabrication techniques
Apparatus operation skills: SEM, TEM, FT-IR, VSM, TGA, and XRD for material characterization. Automated SPME device, commercial SPME device, solid-phase extraction (SPE), and stir bar sorptive extraction (SBSE) for real food samples preparation. Determination of estrogens and polychlorinated biphenyl by using high performance liquid chromatography and gas chromatography and mass spectroscopy (GC-MS), respectively.

Honor and Award:

National graduate scholarship of 2014.
Excellent graduate student of Zhejiang Province of 2015.
Gold Award of Graduate Academic Festival of Ningbo City of 2014.
Practice Excellence Award of Ningbo University of 2013.

Funding list

The Scientific Research Foundation of Graduate School of Ningbo University (No.G13057).

Students’ innovation projects of Zhejiang Province (No.2013R405027).