The Untold Story of False Positives: Strategies to Decrease the Number of False Positives in Pesticide Residue Measurements Using LC-QTOF Mass Spectrometry
The huge benefit of QTOF technology for residue analysis is the possibility of looking for a large number of analytes with almost no method optimisation. But what if among those thousands of compounds analytes with the same elemental composition and similar retention times are present? What if those compounds even show the same fragments?
Finding a strategy for a reduction of false positives is starting to become an important issue.
Dorith Brombach studied chemistry at the Justus-Liebig University in Gießen. She started her PhD in the organic chemistry department under the supervision of Prof Wolfgang Maison. In 2011 the group moved to the university of Hamburg where she finished her PhD with the title “Boronolectins Based on Adamantane Scaffolds for the Recognition of Carbohydrates”. Since 2013 she is working for Bruker Daltonics as an application chemist and is focusing on screening applications using HRES-QTOF technology.